Myosin Light Chain Kinase 480-501 35 leverantörer
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Myosin Light Chain Kinase. Isoforms of myosin light chain kinase (MLCK) exist in smooth and skeletal muscle and in other tissues including the brain. They all exist as monomers that can be quite variable in mass. The smooth muscle forms range in size from approximately 130–210 kDa and the skeletal muscle forms range from 67 to 150 kDa. This diversity in size is the result of mRNA splicing and or/alternative promoter usage in the gene.
– RLC fosforyleras. • Myosinfilament. • ATPase av AK Johnsson · 2011 — The microfilament system, formed by actin, myosin and regulatory proteins, is myosin light chain kinase (MLCK) and Rho associated kinase (ROCK), are able Myosin Light Chain Kinase -- Chapter 10. Myosin Light Chain Phosphatase -- Chapter 11. Calcium/Calmodulin-Dependent Protein Kinase II -- Chapter 12. Kammarmuskelns kontraktionsgrad bestäms av aktiviteten hos MLCK.
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Alternativa namn: N-(4-Aminobutyl)-2-naphthalenesulfonamide hydrochloride. Ansökan A calmodulin antagonist that inhibits myosin light chain kinase. CAS Nr: Species, Score, Bootstrap, Description, Alternative ID. Q15746 · Homo sapiens, 1, 100%, Myosin light chain kinase, smooth muscle, MYLK_HUMAN (UniProt).
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MLCK1 is found in smooth muscle and phosphorylates myosin II regulatory light chains at Ser 19 , and MLCK2 is located in the striated muscle. MW 452.74, Purity > 99%. Potent and selective myosin light chain kinase inhibitor (MLCK) (Ki = 300 nM).
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(2002) Properties of long myosin light chain kinase binding to F-actin in vitro and in vivo. J. Biol. Chem.
my·o·sin light-chain ki·nase [MIM*600922] a calcium/calmodulin-dependent enzyme that phosphorylates the light chains of smooth muscle myosin and initiates contraction; in skeletal muscle, phosphorylation modulates tension during contraction. A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart. J Clin Invest.
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Ansökan A calmodulin antagonist that inhibits myosin light chain kinase. CAS Nr: Species, Score, Bootstrap, Description, Alternative ID. Q15746 · Homo sapiens, 1, 100%, Myosin light chain kinase, smooth muscle, MYLK_HUMAN (UniProt). Epithelial myosin light">light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity* Tumor necrosis factor Abstract [en]. Purpose: Heritable thoracic aortic disease can result from null variants in MYLK, which encodes myosin light-chain kinase (MLCK).
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The muscle contraction pathways regulated by calcium ions show three major mechanisms [11-13]; i) Troponin-tropomyosin complex system which is related to actin-filament in skeletal muscle and cardiac muscle, ii) Myosin light chain kinase mechanism which occurs during muscle contraction with calmodulin in vertebrate's smooth muscles, iii) Calcium ions bind directly to myosin and induce muscle Definition of myosin-light-chain kinase in the Definitions.net dictionary. Meaning of myosin-light-chain kinase. What does myosin-light-chain kinase mean? Information and translations of myosin-light-chain kinase in the most comprehensive dictionary definitions resource on the web.